Long-term Outcome of Gastric Per-Oral Endoscopic Pyloromyotomy in Treatment of Gastroparesis
نویسندگان
چکیده
Background & AimsGastric per oral endoscopic pyloromyotomy (GPOEM) is a promising treatment for gastroparesis. There are few data on the long-term outcomes of this procedure. We investigated GPOEM patients with refractory gastroparesis.MethodsWe conducted retrospective case-series study all who underwent gastroparesis at single center (n = 97), from June 2015 through March 2019; 90 had more than 3 months follow-up and were included in our final analysis. collected cardinal symptom index (GCSI) scores (measurements postprandial fullness or early satiety, nausea vomiting, bloating) SF-36 questionnaire (measures quality life). The primary outcome was clinical response to GPOEM, defined as decrease least 1 point average total GCSI score 25% 2 subscales symptoms. Recurrence return baseline after an initial complete response. secondary factors that predict failure (no recurrence within 6 months).ResultsAt (3 GPOEM), 73 (81.1%) significant increases (indicating increased life) whereas 17 (18.9%) no Six 7.1% recurrence. At 12 months, 8.3% remaining 24 4.8% 36 14.3% For experienced response, rate loss year 12.9%. In univariate multivariate regression analysis, longer duration reduced odds (odds ratio [OR], 0.092; 95% CI, 1.04–1.3; P .001). On logistic regression, high BMIs (OR, 1.097; 1.022–1.176; .010) receiving psychiatric medications higher risk 1.33; 0.110–1.008; .052).ConclusionsIn analysis gastroparesis, 81.1% their 69.1% 85.2% responders maintained Patients improved life long years High BMI associated GPOEM. Gastric months). .052).
منابع مشابه
Gastric per-oral endoscopic pyloromyotomy in the treatment of refractory gastroparesis: Report on the first case performed in Mexico.
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ژورنال
عنوان ژورنال: Clinical Gastroenterology and Hepatology
سال: 2021
ISSN: ['1542-7714', '1542-3565']
DOI: https://doi.org/10.1016/j.cgh.2020.05.039